Related Experiment Video
Updated: May 17, 2025

08:02
A High-Throughput Image-Guided Stereotactic Neuronavigation and Focused Ultrasound System for Blood-Brain Barrier Opening in Rodents
Published on: July 16, 2020
4.7K
Expandable grid, a simple, readily available and precise technique for intraoperative stereotactic real-time imaging
Dirar Aldabek1, Andreas Hodul2, François Alesch3
1Department of Neurosurgery, Heinrich-Braun-Klinikum, Karl-Keil-Straße 35, 08060, Zwickau, Germany.
Acta Neurochirurgica
|April 2, 2025
Summary
This study presents a simple fluoroscopy-based technique for accurate stereotactic surgery planning and validation. The method provides immediate access to stereotactic coordinates with an accuracy of less than 1 mm.
Area of Science:
- Neurosurgery
- Medical Imaging
- Stereotactic Procedures
Background:
- Intraoperative imaging like CT and MRI is crucial for stereotactic procedures but not universally available.
- Microelectrode recording (MER) is also limited to select centers.
- This study proposes fluoroscopy as an accessible alternative for intraoperative control.
Purpose of the Study:
- To introduce and validate a novel fluoroscopy-based technique for stereotactic target planning and coordinate validation.
- To demonstrate the accessibility and accuracy of this method compared to existing modalities.
Main Methods:
- Adapted the Riechert Mundinger (RM) and Zamorano-Dujovny (ZD) stereotactic systems by shifting the Z-value zero point.
- Utilized radiopaque markers and Angio/X-ray localizing plates to create an orthogonal, non-distorted stereotactic space.
- Superimposed magnified millimetric grids on fluoroscopic images for precise coordinate validation in AP and lateral views.
Main Results:
- The technique was validated using phantom conditions and intraoperative fluoroscopic images.
- Results demonstrated high accuracy, with a margin of error below 1 mm.
- The method proved comparable in accuracy to more complex imaging techniques.
Conclusions:
- The developed fluoroscopy technique is accurate, accessible, mobile, and manageable for intraoperative stereotactic guidance.
- It offers immediate access to stereotactic coordinates, enhancing surgical planning and execution.
- This approach provides a cost-effective and efficient alternative to advanced imaging modalities.

