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Evaluation of an Online-Based Self-Help Program for Patients With Panic Disorder: Randomized Controlled Trial
Christopher Lalk1, Teresa Väth1, Sofie Hanraths1
1Clinical Psychology and Psychotherapy of Adulthood, Institute of Psychology, University Osnabrück, Osnabrück, Germany.
Journal of Medical Internet Research
|April 2, 2025
Summary
This online cognitive behavioral therapy (iCBT) program effectively reduced panic disorder and agoraphobia symptoms. While well-being did not improve, the intervention also lowered anxiety and depression in participants.
Area of Science:
- Psychiatry
- Psychology
- Digital Health
Background:
- Panic disorder and agoraphobia are debilitating anxiety disorders impacting well-being.
- Internet-based cognitive behavioral therapy (iCBT) offers a scalable treatment option.
- iCBT can potentially overcome barriers to traditional mental health treatment.
Purpose of the Study:
- To evaluate the effectiveness of a novel online self-help intervention for panic disorder with or without agoraphobia.
- Primary hypotheses focused on improving panic, agoraphobia symptoms, and overall well-being.
- Secondary hypotheses aimed to assess improvements in daily functioning, mental health literacy, work ability, and healthcare utilization.
Main Methods:
- A randomized controlled trial involving 156 German-speaking adults (18-65 years) diagnosed with panic disorder with or without agoraphobia.
- The intervention group (n=82) received a 12-week online program including psychoeducation, cognitive restructuring, exposure, and mindfulness.
- The control group (n=72) received usual care, with the option to access the program post-study. Primary outcomes measured by the Panic and Agoraphobia Scale (PAS) and WHO-5 Well-Being Index.
Main Results:
- Participants completed an average of 7.3 out of 12 modules (60.8%); 32.1% finished the entire course.
- The intervention group showed a significant reduction in PAS scores (P=.03) with a small to moderate effect size (d=-0.37).
- Significant improvements were noted in anxiety (P<.001, d=-0.60) and depression (P<.001, d=-0.41), but not in WHO-5 well-being or secondary outcomes.
Conclusions:
- The online intervention effectively reduced core symptoms of panic disorder and agoraphobia, alongside anxiety and depression.
- No significant effects were observed on well-being or secondary outcomes, potentially influenced by illness burden and the COVID-19 pandemic.
- Further research and intervention adaptations are recommended to enhance outcomes for well-being and other secondary measures.
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