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Applied potential tomography: possible clinical applications.

B H Brown, D C Barber, A D Seagar

    Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Fur Medizinische Physik and the European Federation of Organisations for Medical Physics
    |May 1, 1985
    PubMed
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    Applied potential tomography (APT), an electrical impedance imaging technique, shows promise for dynamic in vivo applications. Its high-speed data collection and sensitivity offer potential for clinical use, particularly in lung imaging and neonatal care.

    Area of Science:

    • Biomedical Engineering
    • Medical Imaging
    • Electrical Impedance Tomography

    Background:

    • Applied potential tomography (APT), also known as electrical impedance imaging, has gained recent attention.
    • In vivo imaging capabilities have been demonstrated, with ongoing research into future applications.

    Purpose of the Study:

    • To review current in vivo results and future prospects of APT.
    • To differentiate between static and dynamic imaging capabilities and applications.

    Main Methods:

    • Review of existing literature and in vivo imaging results.
    • Analysis of system features including tissue contrast, data acquisition speed, sensitivity, resolution, cost, and safety.

    Main Results:

    • APT offers good tissue contrast, high-speed data collection, and sensitivity to resistivity changes.

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  • Current limitations include low spatial resolution, but the system is low-cost and has no known hazards.
  • Dynamic imaging is identified as the most promising approach for near-term clinical application.

    • Conclusions:

    • Dynamic APT shows significant potential for clinical applications, including lung imaging for ventilation and edema monitoring.
    • Further applications include neonatal intraventricular bleeding detection, gastric physiology studies, and potential uses in blood flow measurement, cell counting, and tissue lesion detection.