Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

5.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of ageing on reading acuity and speed in Spanish older adults.

Clinical & experimental optometry·2026
Same author

Contrast Sensitivity Function in Parkinson's Disease: Effects of Illumination and Disease Stage.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same author

Parkinson's disease and reading performance.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2025
Same author

The Impact of Corneal Oedema on UV Light Transmission: An Experimental Study in Porcine Eyes.

Journal of clinical medicine·2024
Same author

Relationship between Choroidal Thickness and Anterior Scleral Thickness in Patients with Keratoconus.

Diagnostics (Basel, Switzerland)·2024
Same author

Randomised trial of three treatments for amblyopia: Vision therapy and patching, perceptual learning and patching alone.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2024

Related Experiment Video

Updated: May 16, 2025

Visualizing Visual Adaptation
04:43

Visualizing Visual Adaptation

Published on: April 24, 2017

8.9K

Age-related changes in contrast sensitivity function under different illumination conditions.

Alba Herrero-Gracia1, Rosa Hernández-Andrés1, Maria José Luque1

  • 1Department of Optics and Optometry and Vision Sciences, University of Valencia, Valencia, Spain.

Clinical & Experimental Optometry
|April 2, 2025
PubMed
Summary
This summary is machine-generated.

Contrast sensitivity function (CSF) declines with age, particularly under mesopic conditions and glare. Testing mesopic CSF in individuals over 50 aids early detection of age-related vision diseases.

Keywords:
Contrast sensitivitygeriatricsglarehealthy ageingillumination

More Related Videos

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
08:54

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Published on: May 26, 2023

1.3K
Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System
09:16

Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System

Published on: May 6, 2015

9.1K

Related Experiment Videos

Last Updated: May 16, 2025

Visualizing Visual Adaptation
04:43

Visualizing Visual Adaptation

Published on: April 24, 2017

8.9K
Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow
08:54

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Published on: May 26, 2023

1.3K
Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System
09:16

Simultaneous ex vivo Functional Testing of Two Retinas by in vivo Electroretinogram System

Published on: May 6, 2015

9.1K

Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Age-related baseline data are crucial for diagnosing vision abnormalities in clinical optometry.
  • Contrast Sensitivity Function (CSF) is vital for detecting age-related vision diseases, but studies often neglect elderly populations.
  • Establishing age-specific CSF data under varied illumination and glare conditions can aid early disease identification.

Purpose of the Study:

  • To evaluate CSF in healthy individuals aged 50-80 years.
  • To generate normative data for the Functional Acuity Contrast Test under different illumination and glare conditions.
  • To assess the impact of age, illumination, and glare on CSF.

Main Methods:

  • CSF was assessed under photopic and mesopic conditions with low (G1) and high (G2) glare.
  • Best-corrected visual acuity (BCVA) was measured using the ETDRS chart.
  • Participants (n=90) were grouped by age: 50-59 (P1), 60-69 (P2), and 70-80 (P3) years.

Main Results:

  • BCVA declined significantly in participants aged 50-69 years.
  • Photopic CSF was optimal with low glare (G1); high glare (G2) exacerbated age-related decline, especially at higher spatial frequencies.
  • Mesopic CSF decreased with age and glare, showing lower sensitivities except at 1.5 c/deg. CSF varied with BCVA, age, and sex.

Conclusions:

  • CSF declines with increasing age, particularly under mesopic conditions.
  • Mesopic CSF testing shows promise for the early detection of age-related eye diseases.
  • Normative data for the Functional Acuity Contrast Test were extended for older adults under varied conditions.