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Updated: May 17, 2025

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Genetics in Kidney Diseases
Samuel Mon-Wei Yu1, Kirk Campbell1
1Nephrology Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Abstract:
With the increasing availability of genetic testing, nephrologists can now incorporate genetic testing results into traditional biochemical profiles and kidney biopsy data to provide more accurate diagnoses. Moreover, if available, therapeutic approaches can be further tailored to individual genetic testing results to avoid unnecessary exposure to prolonged immunosuppressive medications with often undesirable side effects. Identifying new genetic mutations in kidney diseases also opens new avenues to novel drug targets. Here, we present five clinical questions summarizing some genetic kidney diseases and updates.
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