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Spot size matters: enhancing rosacea treatment with pulsed-dye laser
Di Wu1,2, Rong Zeng3, Jianzhou Ye2
1Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, Sichuan, China.
Lasers in Medical Science
|April 2, 2025
Summary
A larger 10-mm spot size on pulsed dye lasers is as effective as a 7-mm spot for treating rosacea, offering a less painful and optimal treatment choice.
Area of Science:
- Dermatology
- Laser Therapy
- Medical Aesthetics
Background:
- Erythematotelangiectatic rosacea (ETR) presents challenges in treatment.
- The impact of pulsed dye laser (PDL) spot size on ETR efficacy is often overlooked.
Purpose of the Study:
- To compare the efficacy and patient experience of 7-mm versus 10-mm spot sizes of a 595-nm PDL for ETR treatment.
- To determine the optimal spot size for PDL therapy in rosacea.
Main Methods:
- Twenty participants with ETR received three PDL treatments at 4-week intervals.
- Each participant had one cheek treated with a 7-mm spot size and the other with a 10-mm spot size.
- Clinical assessments included erythema and telangiectasia scores, VISIA analysis, and patient-reported outcomes (pain, satisfaction).
Main Results:
- Both 7-mm and 10-mm spot sizes significantly improved ETR symptoms (erythema, telangiectasia, overall appearance) after 3 months.
- Participant satisfaction was higher with the 10-mm spot (90%) compared to the 7-mm spot (85%).
- The 10-mm spot size resulted in significantly lower reported pain levels (VAS) than the 7-mm spot size.
Conclusions:
- A 10-mm spot size is a safe and effective option for treating ETR with a 595-nm PDL.
- The larger spot size offers comparable therapeutic efficacy to the smaller spot but with reduced patient discomfort.
- The 10-mm spot size is recommended as the optimal choice for rosacea treatment with PDL.

