Spontaneous Angiographic Disappearance of an Intracranial Aneurysm: A Systematic Review of Cases in the Last Ten Years and Two Cases from Our Institution

Jun Ha Hwang ¹, Hong Bum Kim , Su Hee Cho

⁰Department of Neurological Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

Neurology India +

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April 3, 2025

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Summary

Spontaneous intracranial aneurysm disappearance is rare but involves complex mechanisms. Recurrence is possible, necessitating careful monitoring or intervention for these brain vascular conditions.

Area Of Science

Neurology
Vascular Surgery
Radiology

Background

Spontaneous disappearance of intracranial aneurysms is a rare phenomenon.
Limited data hinders understanding of its pathophysiology.

Purpose Of The Study

To investigate spontaneous angiographic disappearance of intracranial aneurysms over the past decade.
To determine the clinical significance and recurrence patterns of these events.

Main Methods

Systematic PubMed search for spontaneous aneurysm disappearance cases (last 10 years).
Analysis of patient demographics, aneurysm characteristics, and outcomes.
Inclusion of two additional hospital cases for comprehensive review.

Main Results

12 cases identified from literature, predominantly affecting females (10/12).
Unruptured aneurysms were larger and took longer to disappear.
Three patients experienced aneurysm recurrence during follow-up.

Conclusions

Spontaneous aneurysm disappearance involves intricate interactions of thrombosis, vasospasm, and endothelial remodeling.
Recurrence underscores the need for vigilant monitoring or intervention.
Nuanced understanding is crucial for managing these rare cerebrovascular conditions.