Passive ion fluxes across the corneal endothelium
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Updated: Oct 3, 2026

Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
Published on: July 16, 2013
Abstract:
The deepithelialized cornea is mounted in a chamber and perfused on both surfaces by identical closed systems. The technique allows the continuous measurement of the net water flux and the electrical potential across the preparation as well as the steady state flux of radioactive ions. The permeabilities of pairs of ions in the same direction were compared, and they were found to be closely proportional to their free diffusion constants, suggesting that they passed by way of the intercellular spaces. Technical difficulties prevented a valid determination of the existence of active ion transport, but there was no indication of its presence.
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