Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Movement of Organelles and Vesicles

The Movement of Organelles and Vesicles

In eukaryotic cells, cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A multi-centre, phase 1a/1b dose escalation and expansion study of the HER2-directed antibody-drug conjugate T-Bren (BL-M07D1) in advanced breast cancer and other solid tumours.

EBioMedicine·2026

Same author

Safety and efficacy of decompressive craniectomy versus standard craniotomy for large acute epidural haematoma with tentorial herniation in China (PREDICT-AEDH): a nationwide, multicentre, open-label, parallel-group, randomised controlled trial.

The Lancet. Neurology·2026

Same author

Initial Low-Dose Dacomitinib for First-Line Treatment of Patients With EGFR Exon 21-Mutated Non-Small-Cell Lung Cancer.

Clinical Medicine Insights. Oncology·2026

Same author

Differences of the lamina cribrosa between primary open angle glaucoma and non-pathologic high myopia.

International journal of ophthalmology·2026

Same author

SRSF3 determines T<sub>reg</sub> cell fate in antitumor immunity and autoimmunity.

Science advances·2026

Same author

Physical exercise in combination with audiovisual stimulation alleviates cognitive and affective impairments in Alzheimer's disease model mice via restoring lysosomal membrane integrity.

Alzheimer's research & therapy·2026

Same journal

Principles and strategies in cold/hot property studies of traditional Chinese medicine: an evolution from traditional theory to modern elucidation.

Journal of pharmaceutical analysis·2026

Same journal

Halogenated anthraquinones in breast cancer therapy: Structural modifications targeting VEGF-related angiogenesis pathways.

Journal of pharmaceutical analysis·2026

Same journal

Immunocyte senescence: A new perspective on the remodeling of the ovarian cancer microenvironment and therapeutic intervention.

Journal of pharmaceutical analysis·2026

Same journal

Innovative diabetes mellitus treatment strategies: Mesenchymal stem cell-based therapy and its impact on pro- and anti-inflammatory cytokines modulation.

Journal of pharmaceutical analysis·2026

Same journal

SERS detection of osteoarthritis-linked microRNA-204 via a DNAzyme-catalyzed self-amplifying circuit.

Journal of pharmaceutical analysis·2026

Same journal

Recent advances and expanding applications of organoid models in unveiling drug ADME profiles.

Journal of pharmaceutical analysis·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 16, 2025

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

Urease-powered micro/nanomotors: Current progress and challenges.

Wen-Wen Li¹, Zi-Li Yu^1,2, Jun Jia^1,2

¹State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China.

Journal of Pharmaceutical Analysis

|April 3, 2025

Summary

This summary is machine-generated.

Urease-powered micro/nanomotors (UMNMs) offer a biocompatible propulsion method for biomedical applications. This review highlights UMNM advancements in materials, movement control, and clinical potential, addressing challenges for in vivo use.

Keywords:

Biomedicine Drug delivery Imaging Micro/nanomotor Urease

More Related Videos

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

Published on: June 30, 2018

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins

Published on: January 26, 2019

Related Experiment Videos

Last Updated: May 16, 2025

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Light-driven Molecular Motors on Surfaces for Single Molecular Imaging

Published on: March 13, 2019

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

Published on: June 30, 2018

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins

Assembling Molecular Shuttles Powered by Reversibly Attached Kinesins

Published on: January 26, 2019

Area of Science:

Biomedical Engineering
Nanotechnology
Enzyme Engineering

Background:

Enzyme-powered micro/nanomotors (EMNMs) utilize enzyme-catalyzed fuel decomposition for self-propulsion.
Urease-powered MNMs (UMNMs) offer superior biosafety compared to hydrogen peroxide-based systems.
UMNMs show significant potential for various biomedical applications due to their biocompatibility.

Purpose of the Study:

To review recent advancements in urease-powered micro/nanomotors (UMNMs) for biomedical applications.
To focus on materials, movement control, and clinical applications of UMNMs.
To identify challenges and future research directions for UMNM clinical translation.

Main Methods:

Review of diverse materials for UMNM construction.
Analysis of methods for controlling UMNM movement via enzymatic reaction rates.
Exploration of UMNM applications including in vivo imaging, diagnostics, and therapeutics.

Main Results:

Significant progress has been made in developing UMNMs for biomedical uses.
UMNMs are being explored for targeted drug delivery, cancer therapy, and diagnostics.
Key applications include overcoming biological barriers, antibacterial interventions, and managing gastric diseases.

Conclusions:

UMNMs demonstrate immense potential for clinical applications.
Challenges remain in maintaining in vivo activity and achieving precise site-specific targeting.
Further research is needed to overcome these hurdles for practical implementation.