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Gambling disorder comorbidity a narrative review.

Rishi Sharma¹, Aviv Weinstein¹

¹Department of Psychology, Ariel University, Ariel, Israel.

Dialogues in Clinical Neuroscience

|April 3, 2025

Summary

Pathological gambling (PG) frequently co-occurs with other mental health issues like substance use, mood, and anxiety disorders. Effective PG treatment can improve gambling and depressive symptoms, highlighting the importance of addressing these comorbidities.

Keywords:

Gambling disorder alcohol and drug use disorder anxiety comorbidity mood disorders problematic gambling

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Area of Science:

Psychiatry
Behavioral Science
Public Health

Background:

Problematic and pathological gambling (PG) cause significant harm to individuals, families, and society.
PG is highly comorbid with various mental health disorders, complicating treatment and outcomes.

Purpose of the Study:

To review population-based, cross-sectional, treatment, and prospective studies on gambling disorder and its comorbidities.
To synthesize recent findings on the relationship between gambling disorder and other psychiatric conditions.

Main Methods:

A narrative review of studies published over the last 14 years.
Inclusion of diverse study types including population-based, cross-sectional, treatment, and prospective research.

Main Results:

High rates of comorbidity between PG and substance use disorders, mood disorders, and anxiety disorders were observed.
Prospective studies revealed bidirectional temporal relationships between gambling disorder and comorbid conditions.
Women with PG exhibit greater psychiatric comorbidity, including higher rates of mood disorders, suicidality, mania, anxiety, and alcohol dependence.

Conclusions:

Significant advancements in understanding and treating gambling disorder (GD) and its psychiatric comorbidities have been made over the past 15 years.
Evidence underscores the reciprocal nature of the relationship between GD and conditions such as substance use, mood, and anxiety disorders.
Treatment for PG shows efficacy in improving both gambling and depressive symptoms, emphasizing the need for integrated care approaches.