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Factors Affecting Renal Clearance: Renal Impairment

Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...

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M Protein Interference in Renal Function Assays: A Quest for True Kidney Function

Michelle P van der Helm^1,2, Brigitte A Wevers^1,3, Cees van Beek⁴

¹Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center (LUMC), Leiden, the Netherlands.

The Journal of Applied Laboratory Medicine

|April 3, 2025

Summary

No abstract available in PubMed .

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