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Updated: May 16, 2025

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting

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The Effects of Early Oral Intake in the Postanesthesia Care Unit on Nausea and Vomiting: A Meta-analysis of

Mi-Ra Kang1, Hyun-Ju Seo2, Ji Sung Lee3

  • 1Acute Pain Service Team, Department of Nursing, Asan Medical Center, Seoul, South Korea.

Journal of Perianesthesia Nursing : Official Journal of the American Society of Perianesthesia Nurses
|April 3, 2025
PubMed

Insights

Early oral fluid intake in the postanesthesia care unit (PACU) reduces vomiting in pediatric patients after surgery. This practice does not increase nausea, promoting faster recovery.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Evidence-Based Medicine

Background:

  • Postoperative nausea and vomiting (PONV) are common complications in pediatric patients following general anesthesia.
  • Current practices for oral intake in the postanesthesia care unit (PACU) vary, impacting patient recovery.
  • Optimizing early recovery protocols is crucial for pediatric surgical patients.

Purpose of the Study:

  • To systematically review and meta-analyze the impact of early versus delayed oral fluid intake on nausea and vomiting in pediatric patients in the PACU.
  • To assess the safety and efficacy of early oral refeeding post-anesthesia in children.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) conducted up to July 2023.
  • Searched multiple electronic databases (PubMed, CINAHL, Embase, Cochrane CENTRAL, etc.).
  • Assessed risk of bias using the Risk of Bias 2 tool and certainty of evidence with GRADE.

Main Results:

  • Meta-analysis of 6 RCTs (2,723 patients) showed early oral intake significantly decreased vomiting incidence by 36% (RR=0.64, 95% CI: 0.42-0.97) with moderate certainty.
  • Meta-analysis of 3 RCTs (2,185 participants) indicated early oral intake did not increase nausea (95% CI: -0.76-0.07) with low certainty.
  • Evidence suggests early oral fluid intake is associated with reduced vomiting and no increased nausea.

Conclusions:

  • Early oral fluid intake in the PACU is effective in reducing postoperative vomiting in pediatric patients.
  • This intervention does not appear to increase the incidence of postoperative nausea.
  • Healthcare providers should consider implementing early oral fluid intake to enhance recovery in pediatric surgical patients.
Abstract

Keywords:
meta-analysisnauseapediatricssurgeryvomitingwater intake

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