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Patient-Reported Quality-of-Life Outcome Measure After Parotidectomy
Linda X Yin1, Christine M Lohse2, Kathleen J Yost2
1Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, Rochester, Minnesota.
JAMA Otolaryngology-- Head & Neck Surgery
|April 3, 2025
Summary
A new patient-reported quality-of-life (QOL) index for parotidectomy recovery was developed and validated. The Parotidectomy Quality of Life Index shows excellent reliability and validity for assessing patient outcomes after surgery.
Area of Science:
- Oncology
- Surgical Outcomes
- Patient-Reported Outcomes
Background:
- Parotidectomy recovery lacks validated patient-reported quality-of-life (QOL) instruments.
- Existing tools do not fully capture the multidimensional aspects of patient-centered outcomes post-parotidectomy.
Purpose of the Study:
- To establish and validate a comprehensive English-language patient-reported QOL instrument specifically for parotidectomy recovery.
- To develop the Parotidectomy Quality of Life Index (PQOLI).
Main Methods:
- A two-phase survey study was conducted, involving a single-institution cohort and an anonymous web-based survey.
- Exploratory factor analysis, Cronbach α, and intraclass correlation coefficients were used to assess validity and reliability.
- The final instrument was refined to 33 items across 6 domains and 2 standalone items.
Main Results:
- The final Parotidectomy Quality of Life Index includes 33 items across 6 domains, demonstrating excellent internal validity (Cronbach α ≥ 0.77).
- The instrument showed very good test-retest reliability (intraclass correlation coefficients 0.82-0.93).
- Lower QOL scores were associated with younger age and malignant tumors.
Conclusions:
- The Parotidectomy Quality of Life Index is a validated instrument with excellent internal validity and test-retest reliability.
- This tool can aid quality improvement in clinical practice and serve as a key outcome measure in future parotidectomy trials.
- Further external validation is recommended.
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