![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
[18F]FDG PET-CT in Weber-Christian Disease
Vicky Betech-Antar1, Miguel Barrio-Piqueras2, Juan J Rosales1
1Departments of Nuclear Medicine.
Abstract:
A 46-year-old woman with relapsing fever and painful pelvic subcutaneous nodules was referred to our center for a second opinion. Despite antibiotic and corticoid treatment, inflammation markers remained high. FDG-PET/CT was performed to evaluate the possible cause of her clinical condition, exclude systemic disease and evaluate the extension and inflammation of the nodules. FDG-PET/CT showed multiple abdominopelvic subcutaneous soft tissue foci without visceral involvement. The review of a previous nodule biopsy revealed Weber-Christian Disease (WCD), a rare disorder characterized by idiopathic nodular panniculitis, fever, and systemic inflammation. WCD is a diagnosis of exclusion when no other cause of panniculitis can be identified.
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