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Updated: May 16, 2025

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
Published on: July 28, 2021
Electrochemical Detection of Chloramphenicol with Different Modified Electrodes Based on the
Yu-Ying Li1, Xia Niu2, Wen-Yuan Pei1
1Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education, Department of Chemistry, Northeast Normal University, Changchun 130024, China.
Abstract:
Design of high-performance electrochemical sensors for detection of antibiotics is greatly desirable for human health and ecological safety. Herein, a new metal-organic framework (MOF), namely, [Zn2L(PDC)2(H2O)2]·3H2O (1), was synthesized with isophthalic acid (H2PDC), Zn(II) cation, and cyclotriveratrylene-based ligand (L). By mechanical milling, 1 was incorporated with mesoporous carbon (MC) to produce 1@MC. Subsequently, 1@MC was decorated on different bare electrodes (glass carbon (GC), Au, Pt, or W electrode). The introduction of MC significantly improved the conductivity and the current response intensity for determination of chloramphenicol (CAP). Among these sensors, the current responses of CAP on 1@MC(1:2)/GCE and 1@MC(1:2)/Au were more intense. Markedly, they exhibited relatively wide linear ranges (0.5-400 μM on 1@MC(1:2)/GCE and 1-400 μM on 1@MC(1:2)/Au) and low limits of detection (0.15 μM on 1@MC(1:2)/GCE and 0.48 μM on 1@MC(1:2)/Au). Particularly, they can be used for the measurement of CAP in eye drop and milk sample with fine recoveries.
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