Relationship between composite dietary antioxidants index and growth indicators in children aged 3-12 years: results

Rui Wen1, Huanting Pei1, Jingyi Ren1

  • 1Department of Nutrition and Food Hygiene, School of Public Health, Hebei Medical University, Hebei Key Laboratory of Environment and Human Health, Shijiazhuang, China.

PubMed

Insights

Higher intake of dietary antioxidants is linked to better child growth indicators like height and weight. Combining multiple antioxidants may offer synergistic benefits for children's development.

Area of Science:

  • Nutrition Science
  • Pediatric Health
  • Dietary Assessment

Background:

  • Nutrient intake with antioxidant properties impacts health outcomes.
  • Limited evidence exists on antioxidant nutrient intake and children's growth indicators.
  • This study investigates the Composite Dietary Antioxidant Index (CDAI) and child growth.

Purpose of the Study:

  • To examine the association between the Composite Dietary Antioxidant Index (CDAI) and child growth indicators.
  • To analyze the relationship in two distinct cohorts of children.
  • To explore potential gender-specific differences and dose-response relationships.

Main Methods:

  • Cross-sectional analysis using data from CCSMDM (n=1,064) and NHANES (n=2,404) databases.
  • Participants aged 3-12 years.
  • Multinomial logistics regression and restricted cubic splines for association and dose-response analyses, with subgroup analyses by gender.

Main Results:

  • CDAI positively associated with children's height and weight across both cohorts after confounder adjustment.
  • Specific antioxidant nutrients (vitamins A, E, zinc, magnesium, selenium) correlated with height and BMI.
  • A stronger positive association between CDAI and height was observed in male children.

Conclusions:

  • Dietary antioxidant nutrients benefit children's growth indicators, promoting height and weight.
  • Consuming a combination of multiple antioxidants is recommended for potential synergistic effects.
  • Further research is needed to elucidate the mechanisms behind antioxidant synergy in child development.
Abstract

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