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Duodenal Bulb Adenocarcinoma: A Case Report
Mohammad N Kloub1, Abdul-Rahman I Abusalim2, Abdelhadi Farouji1
1Internal Medicine, Saint Michael's Medical Center, Newark, USA.
Cureus
|April 4, 2025
Summary
Adenocarcinoma in the duodenal bulb, the upper part of the small intestine, is extremely rare. This case highlights a rare instance of duodenal bulb adenocarcinoma causing anemia in an elderly patient.
Area of Science:
- Gastroenterology
- Oncology
Background:
- Duodenal adenocarcinoma is the most common small bowel adenocarcinoma, typically affecting the descending duodenum.
- Adenocarcinoma in the duodenal bulb is exceptionally rare.
Observation:
- An 80-year-old female presented with symptomatic anemia.
- The anemia was attributed to gastrointestinal blood loss.
Findings:
- The patient was diagnosed with adenocarcinoma of the duodenal bulb.
- This represents an uncommon site for small intestine adenocarcinoma.
Implications:
- This case underscores the importance of considering rare diagnoses in patients with unexplained GI bleeding and anemia.
- Further research into the etiology and management of duodenal bulb adenocarcinoma may be warranted.

