Rock-on-a-chip: a novel method for designing representative microfluidic platforms based on real rock structures and
Pablo A Godoy1, Alirza Orujov2, Aurora Pérez Gramatges1,3
1Chemistry Department - Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Rio de Janeiro, Brazil. aurora@puc-rio.br.
Lab on a Chip
|April 4, 2025
Summary
This study presents a novel multi-step workflow to accurately replicate complex rock pore structures in 2D microfluidic chips, enhancing studies of porous media for oil recovery and carbon storage.
Area of Science:
- Geosciences
- Engineering
- Physics
Background:
- Microfluidics is crucial for studying pore-scale phenomena in porous media, vital for applications like oil recovery and carbon storage.
- Existing methods struggle to accurately replicate the complex morphology of natural rock pore structures in 2D microfluidic platforms.
Purpose of the Study:
- To develop a robust multi-step workflow for generating quasi-2D microfluidic chips that precisely preserve the pore morphology and size distributions of 3D rock samples.
- To improve the reliability of microfluidic studies by minimizing discrepancies between real pore space and microchip designs.
Main Methods:
- A multi-step workflow was developed to generate 2D pore throats from 3D network data derived from CT-scanned rock samples.
- Precise mask alignment was employed during fabrication to ensure accurate pore geometry, especially for narrow throats.
- Permeability was regulated by adjusting inlet areas while maintaining original pore and throat size distributions.
Main Results:
- The developed method demonstrated strong agreement between 2D and 3D pore and throat size distributions in both designed patterns and fabricated microchips.
- Accurate fabrication of microchips with narrow throats was achieved through precise mask alignment.
- Flow simulations revealed discrepancies between simulated and experimental permeability, particularly in low-permeability designs sensitive to etching.
Conclusions:
- The proposed workflow significantly minimizes common discrepancies between natural rock pore space morphologies and quasi-2D microchips.
- This advancement enhances the reliability of microfluidic studies requiring faithful representation of pore-scale structures.
- The method offers a valuable tool for research in subsurface energy and environmental applications.


