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How green are radiopharmaceutical sciences?

Verena Pichler1, Matthias Manfred Herth2, Verena Hugenberg3

  • 1Department of Pharmaceutical Sciences, Division of Pharmaceutical Chemistry, University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria; Department of Pharmacy, University of Oslo, Sem Sælands vei 3, 0371 Oslo, Norway.

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Radiopharmaceutical sciences need sustainable practices. This study proposes nine tailored green chemistry and engineering principles to reduce waste and energy use in nuclear medicine development.

Keywords:
Energy efficacyGreen chemistrySustainability

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Area of Science:

  • Radiopharmaceutical Sciences
  • Nuclear Medicine
  • Green Chemistry

Background:

  • The radiopharmaceutical sector is rapidly expanding, driven by theranostic agents and PET imaging.
  • Increasing demand presents challenges in energy consumption and waste management for nuclear medicine.
  • The nuclear medicine market is projected to reach $30 billion by 2030.

Purpose of the Study:

  • To examine the applicability of green chemistry and engineering principles in radiopharmaceutical sciences.
  • To propose tailored sustainability principles for the field.
  • To address environmental impact reduction in radiopharmaceutical development.

Main Methods:

  • Review of the 12 principles of green chemistry and engineering.
  • Adaptation of traditional sustainability frameworks for radiopharmaceutical specific needs.
  • Development of nine key principles for sustainable radiopharmaceutical sciences.

Main Results:

  • Identification of specific challenges in applying sustainability to radiopharmaceuticals, including radiation safety, speed, and automation.
  • Proposal of nine tailored principles focusing on waste prevention, radionuclide recycling, energy efficiency, and cleaner irradiation technologies.
  • Emphasis on the need for integrating sustainability into training and research.

Conclusions:

  • Sustainability principles are crucial for the growing field of radiopharmaceutical sciences.
  • Nine adapted principles offer a framework for greener radiopharmaceutical development.
  • Future integration of sustainability into education and research is essential for long-term environmental responsibility.