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Updated: Aug 1, 2026

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Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy
Published on: March 1, 2016
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Engineered heart tissue patches: A milestone in cardiac regenerative medicine
Alain van Mil1, Jasmijn Janssen1, Eva van Rooij2
1Experimental Cardiology Laboratory, Department of Cardiology, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands.
Cell Stem Cell
|April 4, 2025
Abstract:
Researchers have demonstrated that a stem cell-derived heart muscle patch can safely remuscularize failing hearts.1 Published in Nature, the study shows successful long-term cardiac integration of a patch in a primate model and a human patient with no adverse effects. This breakthrough marks a major step toward regenerative therapies for advanced heart failure.

