Related Experiment Video
Updated: May 16, 2025

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
Massive Myocardial Calcification
Mehran Babady1, Charalampia Maltsinioti1, Ermal Limaj1
1Department of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany.
Insights
Massive myocardial calcification is rare, requiring advanced imaging for diagnosis. This case study details a patient
Area of Science:
- Cardiology
- Cardiac Imaging
- Pathology
Background:
- Massive myocardial calcification is an exceptionally rare cardiac condition.
- Diverse etiologies contribute to this pathology.
- Multimodality imaging is crucial for diagnosis.
Observation:
- A 73-year-old woman with coronary artery disease and ovarian carcinoma presented with dizziness and dyspnea.
- Echocardiography revealed extensive myocardial calcification, left ventricular hypertrophy, and a large mobile structure on the mitral leaflet.
- Post-surgery, the patient developed pulmonary hypertension, increased calcification, and right ventricular dysfunction.
Findings:
- Histological examination revealed fibrosis and scarring.
- The etiology of the extensive myocardial calcification remained unclear.
- Hypertrophic cardiomyopathy was considered a potential underlying condition.
Implications:
- This case underscores the importance of multimodality imaging in diagnosing rare cardiac conditions.
- A comprehensive diagnostic workup is vital for effective management.
- This case adds to the limited literature on massive myocardial calcification and its management challenges.
Background:
Massive myocardial calcification is an extremely rare condition with diverse etiologies, often requiring multimodality imaging for diagnosis.
Case Summary:
A 73-year-old woman with coronary artery disease and a history of ovarian carcinoma presented with dizziness and dyspnea. Echocardiography revealed a large floating structure on the anterior mitral leaflet, left ventricular hypertrophy, and extensive myocardial calcification. Preoperative imaging confirmed calcifications, and surgery included decalcification, subvalvular myectomy, and aortic valve replacement. Histology revealed fibrosis and scarring. Four years later, she developed pulmonary hypertension, increased calcification, and right ventricular dysfunction. Despite thorough evaluation, the etiology of the calcification remained unclear, with hypertrophic cardiomyopathy considered a probable underlying condition.
Discussion:
This case highlights a rare presentation of myocardial calcification, emphasizing the value of multimodality imaging and comprehensive diagnostic workup. It contributes to the limited literature on the condition and its management challenges.
Take-Home Messages:
Multimodality imaging and a systematic approach are vital for diagnosing and managing rare cardiac conditions like massive myocardial calcification.
Related Concept Videos
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...

