Massive Myocardial Calcification

Mehran Babady1, Charalampia Maltsinioti1, Ermal Limaj1

  • 1Department of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany.

JACC. Case Reports
|April 4, 2025
PubMed

Insights

Massive myocardial calcification is rare, requiring advanced imaging for diagnosis. This case study details a patient

Area of Science:

  • Cardiology
  • Cardiac Imaging
  • Pathology

Background:

  • Massive myocardial calcification is an exceptionally rare cardiac condition.
  • Diverse etiologies contribute to this pathology.
  • Multimodality imaging is crucial for diagnosis.

Observation:

  • A 73-year-old woman with coronary artery disease and ovarian carcinoma presented with dizziness and dyspnea.
  • Echocardiography revealed extensive myocardial calcification, left ventricular hypertrophy, and a large mobile structure on the mitral leaflet.
  • Post-surgery, the patient developed pulmonary hypertension, increased calcification, and right ventricular dysfunction.

Findings:

  • Histological examination revealed fibrosis and scarring.
  • The etiology of the extensive myocardial calcification remained unclear.
  • Hypertrophic cardiomyopathy was considered a potential underlying condition.

Implications:

  • This case underscores the importance of multimodality imaging in diagnosing rare cardiac conditions.
  • A comprehensive diagnostic workup is vital for effective management.
  • This case adds to the limited literature on massive myocardial calcification and its management challenges.
Abstract