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Updated: May 16, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Optical Coherence Tomography Illustration of Multiple Plaque Erosions and Rupture in Acute Coronary Syndrome
Mohammed Ahmed1, Zhihong Yao2, Khaled Albouaini3
1Department of Cardiology, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom; Liverpool University Hospital NHS Foundation Trust, Liverpool, United Kingdom.
Background:
Multiple plaque ruptures and erosions, both culprit and remote, have been described and illustrated in the context of acute coronary syndrome. However, there is limited evidence for this phenomenon using optical coherence tomography, the highest resolution intracoronary imaging technology.
Case Summary:
In this report, the authors describe by optical coherence tomography, multiple spontaneous plaque erosions and a ruptured plaque, de novo and in-stent, resulting in 2-vessel occlusion in a patient with acute coronary syndrome.
Discussion:
This case confirms, by means of optical coherence tomography, previous reports of multiple nonculprit plaque erosions and rupture in acute coronary syndrome.
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