Patterns and determinants of potentially harmful first aid practices in children with acute poisoning

Kavinda Dayasiri1

  • 1Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Thalagolla Road, PO Box 06, Ragama, Sri Lanka. kavindadayasiri@gmail.com.

BMC Research Notes
|April 4, 2025
PubMed

Insights

Nearly 30% of children under 12 experienced harmful first aid for acute poisoning. Low maternal education, remote healthcare access, and cultural beliefs significantly influenced these dangerous practices.

Area of Science:

  • Pediatric Emergency Medicine
  • Toxicology
  • Public Health

Background:

  • Acute poisoning is a significant concern in children.
  • Inappropriate pre-hospital first aid can worsen outcomes.

Purpose of the Study:

  • To analyze harmful first aid practices in pediatric acute poisoning.
  • To identify factors influencing caregiver pre-hospital management.

Main Methods:

  • Cross-sectional study of 384 children under 12 with acute poisoning.
  • Utilized univariate and multivariate analyses.
  • Incorporated qualitative findings on caregiver decision-making.

Main Results:

  • 29.4% of children received harmful first aid; household chemicals were common agents.
  • Harmful practices linked to low maternal education, remote healthcare access, and cultural beliefs.
  • Qualitative data revealed knowledge gaps and financial/cultural influences.

Conclusions:

  • Targeted interventions are crucial to address knowledge gaps and socio-cultural factors.
  • Improving caregiver education and healthcare access can reduce harmful first aid.
  • Addressing cultural beliefs is essential for effective pre-hospital poisoning management.
Abstract

Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
761
Anticholinesterase Agents: Poisoning and Treatment01:26

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.     
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
761
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.6K
Enhanced Elimination of Poison01:26

Enhanced Elimination of Poison

Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
460
Antidotes01:17

Antidotes

Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
601
Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
917