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Transabdominal photobiomodulation applications: A systematic review and meta-analysis
Ana M Jiménez-García1, Candela Zorzo2,3,4, Alba Gutiérrez-Menéndez3,4
1BRABE Group, Department of Psychology, Faculty of Life and Natural Sciences, University of Nebrija, Madrid, Spain.
Summary
Photobiomodulation (PBM) shows potential in managing obesity by influencing metabolic factors. This review found PBM treatments significantly altered key obesity indicators in both human and animal studies, suggesting a promising therapeutic avenue.
Area of Science:
- Metabolic Science
- Obesity Research
- Photomedicine
Background:
- Obesity is a growing global health concern with complex origins.
- Photobiomodulation (PBM) is being investigated for its potential to modulate adipose tissue metabolism and inflammation.
- Understanding PBM's role in obesity management is crucial for public health.
Purpose of the Study:
- To systematically review and meta-analyze the effects of transabdominal PBM on obesity indicators.
- To assess PBM's impact on physical, psychological, and physiological variables in obesity.
- To synthesize evidence from preclinical and clinical studies on PBM for obesity.
Main Methods:
- Systematic review and meta-analysis of 24 studies (1041 humans, 100 mice).
- Searched PubMed, Web of Science, ScienceDirect, and Scopus databases.
- Utilized R software for statistical analysis and effect size calculation.
Main Results:
- In humans, PBM significantly affected waist circumference, hip circumference, insulin, and triglycerides.
- In animals, PBM significantly altered epididymal adipocyte area, triglycerides, and glucose AUC.
- Statistical significance (p < 0.05) was observed for key metabolic markers in both models.
Conclusions:
- Diverse wavelengths in PBM research are essential for obesity studies.
- Further investigation is needed to fully understand PBM mechanisms and applications in obesity.
- PBM presents novel therapeutic avenues for obesity and its determinants.
