Related Experiment Video
Updated: May 17, 2025

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
Published on: September 12, 2020
Pseudo-orthostatic tremor in a cat
Marende M de Gier1, Dian Schuil2, Laurent Garosi3
1Department of Neurology, Evidensia Small Animal Hospital Hart van Brabant, Waalwijk, The Netherlands.
Abstract:
An 11-month-old male castrated shorthaired cat was presented with a tremor in both pelvic limbs, which only occurred when standing (ie, countering gravity) or during active extension of the stifle. General clinical and neurological examinations were normal aside from the tremor of the pelvic limbs, which disappeared on performing a weight-bearing lifting test. Needle electromyography of both pelvic limbs in the conscious state confirmed a low-frequency (6 Hz) tremor. The cat was diagnosed with pseudo-orthostatic tremor. The tremor amplitude waxed and waned over time. The cat remained ambulatory and playful, but often assumed lateral recumbency and seemed to have difficulty jumping. Treatment with gabapentin (10-20 mg/kg PO q8h) for 3 weeks followed by clonazepam (0.1 mg/kg PO q12h) for 1 day (with unacceptable adverse effects) did not result in improvement.

