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Updated: May 16, 2025

Methods for In Vivo Biomechanical Testing on Brachial Plexus in Neonatal Piglets
Published on: December 19, 2019
Atraumatic Disorders of the Pediatric Spinal Cord and Brachial Plexus
David S Liu1, Anna Rothenberg1, Andrea S Bauer1
1Department of Orthopedic Surgery, Boston Children's Hospital, Boston, MA.
Insights
Pediatric nonobstetric brachial plexus injuries are rare but diverse. This review offers clinicians a foundational guide for managing these complex cases, considering various causes and unique patient presentations.
Area of Science:
- Pediatric Neurology
- Pediatric Orthopedics
- Nerve Injury
Background:
- Brachial plexus birth injury is common, but nonobstetric injuries in children are less frequent.
- Nonobstetric causes include trauma, thoracic outlet syndrome, acute flaccid myelitis, Parsonage-Turner syndrome, and oncologic conditions.
- Each pediatric brachial plexus injury presents uniquely, complicating management and outcome prediction.
Purpose of the Study:
- To provide clinicians with essential information for managing pediatric and adolescent brachial plexus injuries.
- To consolidate knowledge on diverse etiologies of nonobstetric brachial plexus injuries in young patients.
- To establish a basis for appropriate clinical decision-making in complex pediatric brachial plexus cases.
Main Methods:
- Literature review focusing on pediatric nonobstetric brachial plexus injuries.
- Synthesis of information on various etiologies and their clinical presentations.
- Analysis of factors influencing treatment complexity and patient outcomes.
Main Results:
- Nonobstetric brachial plexus injuries in children stem from varied causes, with trauma being most prevalent.
- The clinical presentation and injury patterns are highly individualized.
- Management strategies require careful consideration due to unpredictable outcomes.
Conclusions:
- A comprehensive understanding of diverse etiologies is crucial for effective management.
- Clinicians need a structured approach to address the unique challenges of pediatric nonobstetric brachial plexus injuries.
- This review serves as a resource to guide appropriate clinical care and improve patient outcomes.
Abstract:
While brachial plexus birth injury is a relatively common condition with an incidence of approximately 1.5 in 1,000 live births, pediatric nonobstetric brachial plexus injuries are more rare. Among nonobstetric causes of brachial plexus dysfunction, trauma is the most common, while other etiologies include thoracic outlet syndrome, acute flaccid myelitis, Parsonage-Turner syndrome, and various oncologic etiologies. The presentation and pattern of injury of each patient is unique despite having the commonality of a brachial plexus injury. As such, treatment algorithms can be complex, and outcomes unpredictable. The aim of this review is to provide a basis of information on which a clinician can appropriately manage pediatric or adolescent patients with brachial plexus injuries of various etiologies.
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