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The statistical impact of ROI referencing on quantitative susceptibility mapping

Patrick S Fuchs1, Oliver C Kiersnowski1,2, Carlos Milovic3

  • 1Department of Medical Physics and Biomedical Engineering, University College London, London, UK.

Magma (New York, N.Y.)
|April 5, 2025
PubMed
Summary

Choosing a reference region in quantitative susceptibility mapping (QSM) impacts clinical findings and may introduce bias. Careful selection is crucial, as no single reference region is optimal for all studies.

Keywords:
ANOVAClinical applicationQSMROIReferencingSusceptibilityt test

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