Advancing Upper Gastrointestinal Cancer Detection: A Single-Center Pilot Study Exploring the Potential of Electrical
Hadi Mokhtari Dowlatabad1, Reihane Mahdavi1,2, Seyed Rouhollah Miri2,3
1Nano Bioelectronics Devices Lab (NBEL), Cancer Electronics Research Group, School of Electrical and Computer Engineering, Faculty of Engineering, University of Tehran, P.O. Box, Tehran, 14399-57131, Iran.
Purpose:
Early detection of GI cancer mass is of utmost importance due to the risks of misdiagnoses that occur through standard endoscopic evaluation.
Methods:
In this research, a real-time intra-endoscopic electrical diagnostic probe has been introduced to discriminate high-risk excision-required lesions utilizing a modified endoscopic biopsy forceps as a non-invasive method.
Results:
By testing on 52 patients who had undergone endoscopic biopsy with a total of 18 high-risk lesions, the invented device named Electrical Endoscopic Mass Characterizer (EEMC), showed %94.7 sensitivity, %93.9 specificity, and %94.2 accuracy (p < 0.01) based on histopathological evaluations of removed specimens as the gold standard.
Conclusions:
EEMC can be utilized as a precise complementary device during endoscopic evaluation for improving the accuracy of early-stage GI cancer detection with no interruptions in the routine procedure.
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