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Updated: May 16, 2025

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
Published on: July 29, 2013
Assessment of CT-to-physical density table for multiple image reconstruction functions with a large-bore scanner for
Takuro Okumura1, Akito S Koganezawa2, Takeo Nakashima1
1Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima 734-8551, Japan.
Purpose:
To evaluate the performance of the Aquilion Exceed LB computed tomography (CT) scanner for radiotherapy treatment planning, this study examined the effect of different combinations of the image reconstruction function (IRF) (AiCE and AIDR) and scan parameters on the CT-to-physical density (CT-PD) table and radiation dose in the phantom, and the effect of different object positions on CT values.
Methods:
To investigate IRF's influence on each material, we calculated CT values by varying tube current, pitch, field of view (FOV), and phantom position for each IRF, comparing them with reference values using filtered back projection (FBP). Furthermore, we evaluated changes in depth dose values due to IRF differences using a solid phantom.
Results:
In the combinations of changes in IRF and scan parameters the change in CT value (ΔHU) of each material was within ±10 HU, except for most conditions. The change in physical density (ΔPD) was within ±0.02 g/cm3 for all combinations. For changes in phantom position, ΔHU was within ±25 HU for changes within the scan FOV, except for Bone 200 mg/cc and 1250 mg/cc. In areas outside the scan FOV with an expanded FOV, ΔHU was significantly larger than within the scan FOV. Variations in depth dose for different IRFs using solid phantoms were within ±0.5 %, except at material boundaries.
Conclusion:
Our evaluations of the CT values and dose calculations suggested no need to change the CT-PD table, even with multiple IRFs.
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