Urgent indications for therapeutic Apheresis. Spanish Apheresis Group (GEA). Second edition 2024

The Spanish Apheresis Group (GEA) presents the second edition of the "Urgent Indications for Therapeutic Apheresis" document, updated 12 years after its initial publication. This revision addresses the need to standardize its application, given the variability observed across different centers and the lack of resources in some provinces. A critical review of the most recent scientific evidence was conducted, including the latest edition of the American Society of Apheresis (ASFA) guidelines and other evidence-based recommendations. Through a methodological review and expert consensus, the list of conditions in which therapeutic apheresis-whether plasma exchange, red blood cell exchange, or cytoreductive apheresis-should be considered an urgent treatment has been redefined. This update introduces new indications and clinical scenarios where apheresis can provide significant therapeutic benefits.