Evolution of methylphenidate prescriptions in the region of Occitanie, France, from 2013 to 2021

Attention Deficit Hyperactivity Disorder (ADHD) is a frequent neurodevelopmental disorder with a lasting functional impact. Our objective was to analyze methylphenidate prescription rates between 2013 and 2021 in Occitanie, to study their evolution over time, disparities within the same region, and factors that could influence them.

Data were extracted via the national insurance health data system, the inter-regime consumption data mart of the Occitanie region. Prevalence and incidence data were reported based on population data from NISES within the same territories. Deprivation indices of municipalities and classification of territories according to rurality were used as analysis variables.

Between 2013 and 2021, the overall rate of methylphenidate prescription in Occitanie increased by 97.3% with territorial disparities. In 2019, the prescription prevalence across all age groups studied was 0.19%, and the incidence was 0.06%. The abandonment rate represents 22.32% across all ages. The decrease in deliveries in the second quarter of 2020 coincides with the COVID-19 pandemic.

Our data are consistent with the results observed at the national level, namely an increase in methylphenidate prescriptions of around 12% per year. Similar results are observed in countries using methylphenidate with initially low prescription rates. The level of prescription reached in Occitanie remains significantly lower than that of comparable Occidental countries, with significant territorial disparities.