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Updated: May 17, 2025

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Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
Published on: July 14, 2023
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Differences in symptom clusters based on multidimensional symptom experience and symptom burden in stroke patients
Siyu Zhou1, Dan Yin1, Huijuan He2,3
1School of Nursing, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Scientific Reports
|April 5, 2025
Summary
Understanding stroke symptoms is crucial. This study found that symptom occurrence and burden are best for identifying stroke symptom clusters, guiding future clinical interventions.
Area of Science:
- Neurology
- Clinical Psychology
- Health Services Research
Background:
- Identifying symptom clusters in stroke patients is essential for effective management.
- Previous research has not clearly defined the optimal dimensions (occurrence, severity, distress, burden) for constructing these clusters.
Purpose of the Study:
- To identify and characterize symptom clusters in stroke patients.
- To determine the most suitable symptom dimension for cluster extraction.
Main Methods:
- Exploratory factor analysis was used on data from 656 stroke patients.
- Symptom clusters were analyzed based on occurrence, severity, distress, and symptom burden.
Main Results:
- Four consistent symptom clusters were identified: mood disturbance, physical symptoms, cognitive dysfunction, and speech/swallowing issues.
- Symptom occurrence and symptom burden demonstrated high consistency across dimensions for cluster identification.
Conclusions:
- Symptom occurrence and symptom burden are recommended for identifying stroke symptom clusters.
- Further research using these dimensions will support clinical interventions and scientific understanding.
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