Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Standard Precaution01:26

Standard Precaution

1.8K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
1.8K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

2.3K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.3K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

3.9K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
3.9K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.2K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.2K
Infection01:20

Infection

6.9K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
6.9K
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

6.5K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cindynics is de rigueur in laboratories and hospital units<sup>✰</sup>.

Presse medicale (Paris, France : 1983)·2026
Same author

Measures to strengthen international biosafety and biosecurity practices.

PLoS biology·2026
Same author

[From vaccination to smallpox eradication].

La Revue du praticien·2025
Same author

The dangerous biology of pathogenic germs.

Comptes rendus biologies·2024
Same author

[In the wake of Alphonse Laveran].

Medecine tropicale et sante internationale·2023
Same author

[From the origin of Sars-CoV-2 to dangerous virology/biology].

Bulletin de l'Academie nationale de medecine·2023

Related Experiment Video

Updated: May 16, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures
09:54

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures

Published on: October 3, 2016

35.8K

Laboratory-associated infections and biosafety.

Patrick Berche1

  • 1Premeritus of microbiology, Université Paris Cité, 85 boulevard Saint-Germain, 75006, Paris, France.

Presse Medicale (Paris, France : 1983)
|April 6, 2025
PubMed
Summary

Laboratory-associated infections pose significant risks. Human error causes most incidents, highlighting the need for mandatory reporting to improve safety and prevent pathogen exposure.

Keywords:
AidsBrucellosisDecontamination accidentsHemorrhagic feversHepatitisHigh-security laboratoriesLaboratory accidentsLaboratory leaksQ feverSarsTuberculosisVenezuelan equine encephalitis

More Related Videos

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
11:13

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology

Published on: October 3, 2016

14.1K
Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 2. General Practices
08:53

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 2. General Practices

Published on: October 3, 2016

17.9K

Related Experiment Videos

Last Updated: May 16, 2025

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures
09:54

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 1. Biosafety Level 4 Suit Laboratory Suite Entry and Exit Procedures

Published on: October 3, 2016

35.8K
Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology
11:13

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 3. Aerobiology

Published on: October 3, 2016

14.1K
Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 2. General Practices
08:53

Safety Precautions and Operating Procedures in an ABSL-4 Laboratory: 2. General Practices

Published on: October 3, 2016

17.9K

Area of Science:

  • Occupational health and safety
  • Infectious disease epidemiology
  • Laboratory biosafety

Background:

  • Laboratory-associated infections (LAIs) from handling pathogens threaten workers and the public.
  • Risks exist in clinical, research, and industrial settings, including vaccine production.
  • Current data collection relies on voluntary reports and retrospective analysis, limiting accurate risk assessment.

Purpose of the Study:

  • To investigate the causes and modes of transmission of laboratory-associated infections.
  • To emphasize the need for mandatory reporting systems for laboratory accidents and exposures.
  • To improve the prevention of laboratory-acquired infections and accidental releases.

Main Methods:

  • Retrospective analysis of published reports on laboratory-associated infections.
  • Review of voluntary questionnaires detailing incidents and exposures.
  • Identification of common pathogens, error types, and contamination routes.

Main Results:

  • Bacteria, viruses (including dangerous ones like filovirus), fungi, parasites, and prions are implicated in LAIs.
  • Human error accounts for approximately 70% of reported incidents.
  • Inhalation of aerosols and accidental parenteral injections are primary contamination routes.

Conclusions:

  • Mandatory reporting of all laboratory incidents involving pathogens is crucial for systematic monitoring and data analysis.
  • Improved data collection will enhance educational efforts and strengthen prevention strategies for laboratory biosafety.
  • Implementing compulsory reporting is essential to mitigate risks associated with handling infectious agents in laboratory environments.