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Related Experiment Videos

Migration and death from malignant melanoma.

K R Cooke, J Fraser

    International Journal of Cancer
    |August 15, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Malignant melanoma mortality rates in New Zealand immigrants were examined. European immigrants had similar rates to their home countries, but early migration from the British Isles correlated with lower rates, possibly due to fewer moles.

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    CJEM·2022

    Area of Science:

    • Epidemiology
    • Dermatology
    • Public Health

    Background:

    • Malignant melanoma of the skin poses a significant public health concern.
    • Understanding risk factors for melanoma in diverse populations, including immigrants, is crucial for targeted prevention strategies.

    Purpose of the Study:

    • To compare age-standardized mortality rates of malignant melanoma in immigrants to New Zealand versus New Zealand-born non-Maori individuals.
    • To investigate the influence of country of origin and age at migration on melanoma mortality.
    • To explore potential mediating factors such as mole frequency and sunburn history.

    Main Methods:

    • Comparative analysis of mortality data for malignant melanoma.
    • Stratification by immigrant status, country of origin, and age at migration.

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  • Community survey to assess phenotypic characteristics (sunburn, moles) in British immigrants and New Zealand-born non-Maoris.

    • Main Results:

    • Immigrants from European countries generally exhibited melanoma mortality rates similar to their countries of origin.
    • Immigrants from the British Isles who migrated at an early age had melanoma mortality rates comparable to New Zealand-born non-Maoris.
    • British immigrants reported fewer moles than New Zealand-born non-Maoris, despite similar rates of severe sunburn.

    Conclusions:

    • Melanoma mortality rates in immigrants are influenced by their country of origin and age at migration.
    • Differences in mole frequency may partially explain the observed variations in melanoma mortality and the effect of age at migration.
    • Further research into genetic and environmental factors influencing mole development and melanoma risk in migrant populations is warranted.