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Small Intestinal Bacterial Overgrowth in a Healthy Female Patient Caused by Long-term Oral Proton Pump Inhibitor
Koichi Soga1, Sotaro Yamada1, Yuto Suzuki1
1Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.
None:
Small-intestinal bacterial overgrowth (SIBO) causes gastrointestinal symptoms. Proton pump inhibitors (PPIs) are commonly used for acid peptic diseases; however, their long-term use can alter the gut microbiota, resulting in adverse effects. We herein report the case of a 26-year-old Japanese woman with SIBO caused by prolonged PPI use. After switching to a H2 receptor antagonist, her symptoms and blood test results improved. This case highlights the need to understand the pathogenesis of SIBO and also the risks associated with prolonged PPI use.
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