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Updated: Jun 16, 2025

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Utility of High-Sensitivity Cardiac Troponin Monitoring in Thoracic Surgery for Predicting Severe Postoperative

Javier J Mateos1, Elena De la Fuente1, Pablo Valero1

  • 1Department of Anesthesiology and Reanimation, Gregorio Marañón General University Hospital, Madrid, Spain.

Journal of Cardiothoracic and Vascular Anesthesia
|April 6, 2025
PubMed

Insights

High-sensitivity cardiac troponin (hs-cTn) monitoring after thoracic surgery can predict severe postoperative complications. Elevated perioperative hs-cTnI levels indicate worse outcomes and higher morbidity.

Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Biomarkers

Background:

  • High-sensitivity cardiac troponin (hs-cTn) monitoring is increasingly used in clinical practice.
  • Predicting severe postoperative complications (sPOCs) in thoracic surgery remains a challenge.

Purpose of the Study:

  • To evaluate the utility of hs-cTn monitoring in predicting sPOCs after lung resection.
  • To correlate hs-cTn levels with postoperative outcomes and preoperative morbidity.

Main Methods:

  • Retrospective observational cohort study of 220 lung resection patients.
  • Measurement of hs-cTnI preoperatively and within 24 hours postoperatively.
  • Analysis of hs-cTnI levels in relation to sPOCs (Clavien-Dindo classification) and survival.

Main Results:

  • Patients with sPOCs exhibited higher pre- and postoperative hs-cTnI levels.
  • Myocardial injury (MI) defined by hs-cTnI > 26.2 ng/L was associated with increased POC incidence.
  • Undetectable preoperative hs-cTnI correlated with improved survival.

Conclusions:

  • Perioperative troponin elevation is linked to adverse short-term outcomes, including sPOCs and extended hospital stays.
  • Preoperative hs-cTnI levels may reflect preoperative patient frailty and morbidity.
Abstract

Keywords:
myocardial injuryperioperativepostoperative complicationsthoracic surgerytroponin

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