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[Resection of Oligometastasis Liver Metastases from Breast Cancer-Two-Case Report]
Yusuke Nishio1, Satoshi Matsukuma, Shigeru Yamamoto
1Dept. of Surgery, JCHO Tokuyama Central Hospital.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|April 7, 2025
Summary
Resection of liver metastases in breast cancer may be beneficial in select cases. Two patients with isolated liver metastases from breast cancer achieved recurrence-free survival after surgical resection.
Area of Science:
- Oncology
- Surgical Oncology
- Breast Cancer Research
Background:
- Resection of liver metastases from breast cancer lacks widespread acceptance due to unproven survival benefits.
- Surgical intervention for liver metastases is considered in specific clinical scenarios.
Purpose of the Study:
- To present two cases of successful liver metastasis resection in breast cancer patients.
- To evaluate the outcomes of surgical resection for isolated liver metastases from breast cancer.
Main Methods:
- Case report of two female patients undergoing resection of liver metastases.
- Detailed analysis of patient demographics, tumor characteristics (HER2 status, hormone receptor status), treatment history, and surgical outcomes.
Main Results:
- Case 1: HER2-positive breast cancer with a single liver metastasis, HER2 negativity confirmed post-resection, recurrence-free at 5 months.
- Case 2: Hormone receptor-positive breast cancer with a single liver metastasis occurring 28 years post-primary resection, complete pathological response, recurrence-free at 1 year.
Conclusions:
- Surgical resection can be a viable option for selected patients with isolated liver metastases from breast cancer.
- Complete pathological response and prolonged recurrence-free survival were observed in both presented cases post-resection.
