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Updated: May 15, 2025
Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Exploring a Water-Ethyl Acetate System for the Efficient Synthesis of 4-Aryl Quinolines
Mohammad Qandalee1, Aliyeh Khajeh-Khezri2, Mohammad Alikarami3
1Department of Basic Sciences Garmsar Branch, Islamic Azad University, Garmsar, 3581631167, Iran.
None:
Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which raise environmental and health concerns while requiring high energy inputs. This study addresses these challenges by applying the principles of green chemistry to develop a sustainable, efficient, and environmentally friendly synthetic route for aryl quinolines.
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