Clinical Features and Outcomes of Pediatric Intraspinal Paragonimiasis

Area of Science:

• Neurology
• Infectious Diseases
• Parasitology

Background:

• Ectopic paragonimiasis can cause severe central nervous system infections.
• Intraspinal paragonimiasis is an uncommon but serious manifestation.
• Pediatric cases require specific diagnostic and treatment considerations.

Purpose of the Study:

• To analyze diagnostic and treatment experiences for pediatric intraspinal paragonimiasis.
• To describe clinical presentation and imaging findings.
• To evaluate treatment outcomes and surgical necessity.

Main Methods:

• Retrospective analysis of pediatric patients hospitalized between 2015-2021.
• Review of clinical symptoms, spinal MRI findings, and treatment regimens.
• Assessment of patient recovery and long-term sequelae.

Main Results:

• Nine pediatric patients were included, with a median age of 9 years.
• Common symptoms included weakness, sensory disturbances, and urinary retention.
• Thoracic spinal extradural enhancing lesions were most common; praziquantel was effective, with 7/9 patients recovering fully.

Conclusions:

• Pediatric intraspinal paragonimiasis predominantly affects the thoracic spine.
• Weakness is the most frequent symptom, alongside potential sensory and sphincter issues.
• Praziquantel monotherapy is effective, and surgical intervention is typically not required.