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Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
A Rare Case of Spontaneous Healing of an Anterior Cruciate Ligament Tear
Daniel R Baka1, Erastus Thuo1, Veniamin Barshay2
1Orthopaedics, Cooper University Hospital, Camden, USA.
Abstract:
Anterior cruciate ligament (ACL) injuries are among the most common knee injuries in the United States. The ACL is an intra-articular ligament that resists anterior tibial translation and provides rotational stability. Most ACL injuries occur through non-contact mechanisms and are typically diagnosed based on history, physical examination, and confirmatory MRI. Treatment options include operative and non-operative management, with the latter focusing on restoring functional stability rather than expecting the ACL to heal spontaneously. In this case report, we present a 33-year-old female patient with a sedentary lifestyle who experienced a popping sensation and immediate swelling after twisting her knee while sitting down. She presented to the clinic one week later, reporting knee instability and a dull, aching pain rated 7/10. Physical examination revealed pain with passive knee extension and positive patellar compression, Clarke's inhibition, McMurray's, and Lachman's tests. MRI confirmed a complete ACL tear and a full-thickness cartilage defect in the medial facet of the patella. The patient opted for non-operative treatment, including a crossover knee brace and physical therapy. Over multiple follow-up visits, her range of motion and pain improved. Eleven months post-injury, a follow-up MRI ordered to evaluate a suspected reinjury unexpectedly revealed a completely intact ACL, indicating spontaneous healing. This case highlights a rare instance of spontaneous ACL healing in a sedentary adult who chose conservative management. Although non-operative therapy typically aims to restore function rather than facilitate ligament healing, emerging evidence suggests spontaneous ACL healing is possible, particularly in proximal femoral single-bundle tears. Further research is needed to establish standardized conservative treatment protocols that optimize outcomes and promote ACL regeneration.
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