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Structured home-based exercise programme and concentric versus eccentric-based stair training programme for pain and
Kazi Md Azman Hossain1, Feroz Kabir1,2, Sharmila Jahan1
1Department of Physiotherapy and Rehabilitation, Jashore University of Science and Technology, Jashore, Bangladesh.
BMJ Open Sport & Exercise Medicine
|April 7, 2025
Summary
This study evaluates structured home-based exercise programs for knee osteoarthritis (OA). It compares a home exercise program (HEP) and stair training programs (concentric vs. eccentric) to improve pain and function in knee OA patients.
Area of Science:
- Orthopedics
- Rehabilitation Medicine
- Clinical Trials
Background:
- Knee osteoarthritis (OA) is a major cause of global pain and disability.
- Exercise is vital for OA management, but optimal home-based programs require further evidence.
- Existing exercise protocols for knee OA need structured, evidence-based validation.
Purpose of the Study:
- To evaluate the effectiveness of a structured home-based exercise program (HEP) for knee OA.
- To compare concentric-based stair training program (CSTP) versus eccentric-based stair training program (ESTP) in knee OA.
- To develop an evidence-based approach for managing knee OA through structured exercise.
Main Methods:
- A two-phase, participant and assessor-blinded, randomized controlled trial involving 247 knee OA participants.
- Phase I: 8-week comparison of HEP versus a control group.
- Phase II: 8-week comparison of CSTP, ESTP, and a control group, with a 24-week follow-up.
Main Results:
- Primary outcomes include pain intensity, pressure pain threshold, and functional ability (WOMAC).
- Secondary outcomes encompass muscle strength, range of motion, aerobic capacity, and quality of life.
- Measurements taken at baseline, post-intervention (two stages), and follow-up.
Conclusions:
- The study aims to provide evidence for effective home-based exercise interventions for knee OA.
- Findings will inform the development of structured exercise programs to manage knee OA symptoms.
- Results will guide clinical practice and patient self-management strategies for knee OA.

