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Evaluating the Volume of Eyes With Pathologic Myopia Using 3D MRI
Tomonari Takahashi1, Tae Yokoi-Igarashi1, Hiroyuki Takahashi1
1Department of Ophthalmology and Visual Science, Institute of Science Tokyo, Tokyo, Japan.
Investigative Ophthalmology & Visual Science
|April 7, 2025
Summary
High myopia (HM) eyes are larger than non-HM eyes and associated with posterior curvature, but not staphyloma presence. This suggests HM eye expansion is not directly linked to posterior staphyloma development.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biometry
Background:
- High myopia (HM) is a significant risk factor for serious ocular pathologies.
- Understanding ocular dimensions is crucial for managing HM complications.
Purpose of the Study:
- To quantify eye volume in high myopia (HM) patients.
- To investigate the relationship between eye volume, posterior curvature, and posterior staphyloma in HM.
Main Methods:
- Three-dimensional magnetic resonance imaging (3D MRI) was used to measure ocular volume in 370 HM eyes and 44 control eyes.
- Eye shapes were classified based on posterior curvature symmetry and steepness.
- The presence of posterior staphyloma was assessed in HM eyes.
Main Results:
- HM eyes exhibited a significantly larger mean volume (12.42 ± 2.40 mL) compared to non-HM eyes (9.67 ± 1.41 mL).
- Eye volume varied with shape: smaller in cylindrical and larger in barrel-shaped eyes.
- No significant difference in mean eye volume was found between HM eyes with and without posterior staphyloma.
Conclusions:
- Increased eye volume in HM is linked to posterior curvature but not directly to posterior staphyloma formation.
- Posterior staphylomas in HM may arise from localized wall weakness rather than global eye expansion.
- Specific monitoring of posterior staphylomas in HM patients is warranted.
