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A Technical Guide for Performing Spectroscopic Measurements on Metal-Organic Frameworks
Published on: April 28, 2023
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A Review on the Recent Progress of Metal-Organic Frameworks Based Surface Enhanced Raman Scattering Sensors
Fengqin Wang1, Jiayi Liu2, Qian Ren1
1College of Chemistry, Tiangong University, Tianjin 300387, P.R. China.
ACS Applied Materials & Interfaces
|April 7, 2025
Summary
Metal-organic frameworks (MOFs) combined with noble metal nanoparticles (MNPs) create advanced Surface-Enhanced Raman Scattering (SERS) substrates. These MOF-based materials offer superior analyte detection for environmental and safety applications.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Surface-Enhanced Raman Scattering (SERS) is a key spectroscopic technique for analyte detection.
- Metal-Organic Frameworks (MOFs) are emerging as effective platforms for SERS substrates.
- MOF-based SERS materials (MNPs/MOFs) demonstrate enhanced sensing capabilities.
Purpose of the Study:
- To review the progress of MOF-metal nanoparticle (MNP) composites for SERS applications.
- To focus on classification, synthesis strategies, and diverse applications of these composite materials.
Main Methods:
- Integration of noble metal nanoparticles (NPs) within MOF structures.
- Development of MOF-based SERS-active materials (MNPs/MOFs).
- Review of existing literature on MNPs/MOFs synthesis and performance.
Main Results:
- MOFs provide porous structures for efficient analyte capture.
- MOF shells protect embedded NPs from degradation, ensuring substrate consistency.
- MNPs/MOFs exhibit enhanced sensing performance compared to traditional SERS substrates.
Conclusions:
- MNPs/MOFs composites represent a significant advancement in SERS technology.
- These materials show great promise for applications in environmental analysis, real-time monitoring, and food safety.
- Further research into synthesis and application is warranted.

