A Review on the Recent Progress of Metal-Organic Frameworks Based Surface Enhanced Raman Scattering Sensors

Surface enhanced Raman scattering (SERS) has evolved into a significant fingerprint spectroscopic technique for rapidly and nonintrusively tracing target analytes through effective SERS substrates. Metal-organic frameworks (MOFs), as a boom crystalline porous material, serve as promising SERS substrates by accommodating noble metal nanoparticles (NPs) to produce MOFs-based SERS-active materials. Recently, MOFs-based SERS materials (MNPs/MOFs) have gained significant attention due to their enhanced sensing performance. The unique porous nature of MOFs provides an efficient capture capability for analytes, while their shells prevent NPs from oxidization and corrosion, thereby enhancing the consistency of SERS substrates. So far, numerous MNPs/MOFs sensors have been documented. This review outlines the research progress of MNPs/MOFs composites, focusing on the classification, synthesis strategies, and applications in environment analysis, real-time monitoring, food safety, etc.