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Updated: May 17, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Post-vitrectomy endophthalmitis complicated with orbital cellulitis treated with hyperbaric oxygen therapy: A case
Yi-Ju Shen1, Li-Ching Liu1, I-Chia Liang1,2
1Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, (R.O.C).
Rationale:
Infectious endophthalmitis developed in silicone oil (SO)-filled eyes after pars plana vitrectomy is a very rare but serious complication. Hyperbaric oxygen therapy (HBOT) has been reported to be effective in few studies of infectious endophthalmitis and orbital cellulitis.
Patient Concerns:
This study reported a case of 71-year-old female with swelling of her left eye 1 week after pars plana vitrectomy and SO tamponade.
Diagnoses:
Acute infectious endophthalmitis complicated with orbital cellulitis and compartment syndrome in a postvitrectomy SO-filled eye.
Interventions:
Intravitreal injection of antibiotics and HBOT.
Outcomes:
The severe inflammatory condition of soft tissue with compartment syndrome and elevated intraocular pressure which could not be controlled ameliorated markedly after initiation of HBOT.
Lessons:
By taking advantages of the features of HBOT, it may be a good adjuvant treatment option for endophthalmitis cases along with antibiotics and surgical therapy.
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