Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

4.8K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
4.8K
What is Genetic Engineering?00:49

What is Genetic Engineering?

72.8K
Overview
72.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Generating cisgenic sexing strains in insect pests.

Communications biology·2026
Same author

Detection of sex chromosomes in Tephritid pests using R-CQ and KAMY, two computational methods to support generic pest management applications.

Insect science·2025
Same author

Engineering new clustered regularly interspaced short palindromic repeats-mediated population control for tephritid pests.

Current opinion in insect science·2025
Same author

A self-limiting sterile insect technique alternative for Ceratitis capitata.

BMC biology·2025
Same author

A higher-yield hybrid rice is achieved by assimilating a dominant heterotic gene in inbred parental lines.

Plant biotechnology journal·2024
Same author

Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata.

Nature communications·2024

Related Experiment Video

Updated: May 15, 2025

Author Spotlight: Optimizing Embryo Microinjection for Transgenesis in Drosophila
05:32

Author Spotlight: Optimizing Embryo Microinjection for Transgenesis in Drosophila

Published on: June 7, 2024

1.7K

Genetic engineering for SIT application: a fruit fly-focused review.

Serafima Davydova1, Danheng Yu1, Angela Meccariello1

  • 1Department of Life Sciences, Imperial College London, London, United Kingdom.

Insect Science
|April 8, 2025
PubMed
Summary

Genetic engineering enhances the sterile insect technique (SIT) for fruit fly pest control. Novel strategies like sexing strains and gene drives offer improved population management in agriculture.

Keywords:
CRISPR/Cas9DrosophilidaeTephritidaeagricultural pestpopulation control

More Related Videos

Protocols for CRISPR/Cas9 Mutagenesis of the Oriental Fruit Fly Bactrocera dorsalis
08:19

Protocols for CRISPR/Cas9 Mutagenesis of the Oriental Fruit Fly Bactrocera dorsalis

Published on: September 28, 2022

2.2K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
00:06

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

13.5K

Related Experiment Videos

Last Updated: May 15, 2025

Author Spotlight: Optimizing Embryo Microinjection for Transgenesis in Drosophila
05:32

Author Spotlight: Optimizing Embryo Microinjection for Transgenesis in Drosophila

Published on: June 7, 2024

1.7K
Protocols for CRISPR/Cas9 Mutagenesis of the Oriental Fruit Fly Bactrocera dorsalis
08:19

Protocols for CRISPR/Cas9 Mutagenesis of the Oriental Fruit Fly Bactrocera dorsalis

Published on: September 28, 2022

2.2K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
00:06

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

13.5K

Area of Science:

  • Agricultural Entomology
  • Genetics and Genetic Engineering

Background:

  • Fruit fly pests (Drosophilidae, Tephritidae) pose increasing threats to agriculture, exacerbated by climate change and globalization.
  • The sterile insect technique (SIT) is a crucial component of integrated pest management strategies.

Purpose of the Study:

  • To review advances in genetic engineering for improving SIT-based fruit fly pest control.
  • To explore novel genetic strategies for enhanced pest population management.

Main Methods:

  • Review of genetic engineering techniques applied to SIT.
  • Discussion of strategies including genetic sexing strains, female lethality, sex distorters, gene drives, and CRISPR/Cas9-based approaches.
  • Illustration using examples from fruit fly pests and model species.

Main Results:

  • Genetic engineering offers diverse strategies to enhance SIT effectiveness.
  • Novel approaches like X-shredding, X-poisoning, gene drives, and precision-guided SIT show potential for modulating population control.
  • The intensity of population control can be adjusted by selecting specific genetic strategies.

Conclusions:

  • Genetic engineering significantly advances SIT for effective fruit fly pest control.
  • Tailored genetic strategies enable precise modulation of pest populations, offering sustainable agricultural solutions.
  • Continued research in genetic tools promises more efficient and targeted pest management systems.