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Author Spotlight: Insights into an Efficient Murine Maxillary Orthodontic Model Protocol
Published on: October 27, 2023
Research progress in periodontally accelerated osteogenic orthodontics
Yichen Xiong1, Jun Chen2,3, Wenjie Li4,5
1Xiangya School of Stomatology, Central South University; Hunan Engineering Research Center for Oral Digitizatize and Personalize Diagnostic and Therapeutic Technology; Hunan Key Laboratory of Oral Health Research; Hunan Clinical Research Center of Oral Major Diseases and Oral Health; Academician Wang Songling Expert Workstation of Oral and Maxillofacial Regeneration, Changsha 410078. xyc0628@csu.edu.cn.
Periodontally accelerated osteogenic orthodontics (PAOO) enhances osteoclast activity to shorten orthodontic treatment. Innovations in surgical techniques and materials are making PAOO less invasive and more effective, though more research is needed.
Area of Science:
- Orthodontics
- Periodontology
- Oral Surgery
- Biomaterials
Background:
- Periodontally accelerated osteogenic orthodontics (PAOO) leverages the regional acceleratory phenomenon (RAP) to expedite orthodontic treatment.
- The primary goal of PAOO is to reduce overall treatment time by stimulating bone remodeling.
- PAOO is an adjunctive therapy used alongside traditional orthodontic interventions.
Purpose of the Study:
- To review recent advancements in PAOO surgical techniques and biomaterials.
- To discuss the trend towards less invasive and more effective PAOO procedures.
- To highlight the need for further clinical research, particularly large-scale randomized controlled trials.
Main Methods:
- Review of recent innovations in PAOO surgical approaches, including piezosurgical corticotomy and alveolar micro-osteoperforations.
- Analysis of novel grafting materials (e.g., bioactive glass) and barrier membranes (e.g., platelet-rich fibrin) used in PAOO.
- Synthesis of current clinical trends and evidence regarding PAOO efficacy and patient experience.
Main Results:
- PAOO surgical techniques have been refined, leading to improved outcomes.
- Advancements in biomaterials enhance the efficacy and biocompatibility of PAOO procedures.
- Current innovations are driving PAOO towards being minimally painful, minimally invasive, and highly effective.
Conclusions:
- PAOO is evolving with optimized surgical methods and advanced biomaterials.
- The trend in PAOO is towards enhanced efficacy with reduced patient discomfort and invasiveness.
- Further high-quality clinical research, including multicenter randomized controlled trials, is essential to validate different PAOO techniques and materials.

