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Updated: Jul 9, 2026

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
Primary cerebral lymphoma and autoimmune hepatitis: an unusual case associated with prolonged treatment with
María Aragüés Floristán1, Marta Obra Pinacho2, Adolfo Jesús Sáez Marín3
1Aparato Digestivo, Hospital Universitario 12 de Octubre, Spain.
Abstract:
The initial approach to autoimmune hepatitis is based on the use of immunosuppressants and corticosteroids. The first-line immunosuppression options include azathioprine or mycophenolate mofetil. Long-term immunosuppression predisposes patients to the development of neoplastic diseases. In this case, chronic AIH treatment with mycophenolate mofetil was associated with the onset of primary cerebral lymphoma, which was treated with methotrexate and rituximab. Rituximab is an interesting therapy for AIH, and in this case, it was able to treat both conditions.
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