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Updated: May 15, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Gut Microbiota Modulation Through Dietary Approaches Targeting Better Health During Metabolic Disorders.
Amit Kumar Rai1, Monika Yadav2, Raj Kumar Duary3
1BRIC-National Agri-Food and Biomanufacturing Institute (BRIC-NABI), SAS Nagar, Mohali, India.
The gut microbiota, an emerging metabolic organ, significantly impacts health. This review explores lactic acid bacteria, probiotics, prebiotics, and fermented foods for improving metabolism and addressing disorders like obesity and hypertension.
Area of Science:
- Microbiology
- Metabolism
- Nutrition Science
Background:
- Gut microbiota plays a crucial role in host metabolism and overall health.
- Dietary habits, lifestyle, and environmental factors significantly influence gut microbiota composition.
- The gut microbiota is increasingly recognized as a key metabolic organ.
Purpose of the Study:
- To review the significance of lactic acid bacteria within the gut microbiota.
- To explore the roles of probiotics, prebiotics, and polyphenols in enhancing human health and metabolism.
- To discuss the implications of gut microbiota in metabolic disorders and therapeutic strategies.
Main Methods:
- Literature review focusing on gut microbiota, lactic acid bacteria, probiotics, prebiotics, polyphenols, and fermented foods.
- Analysis of the relationship between gut microbiota composition and metabolic health.
- Examination of the role of gut microbiota in various metabolic disorders.
Main Results:
- Lactic acid bacteria are key inhabitants of the gut microbiota with significant health implications.
- Probiotics, prebiotics, polyphenols, and fermented foods can positively modulate gut microbiota.
- Gut microbiota alterations are linked to metabolic disorders including dyslipidemia, obesity, hypercholesterolemia, cancer, and hypertension.
Conclusions:
- Modulating gut microbiota through diet and targeted interventions offers therapeutic potential for metabolic disorders.
- Fermented foods serve as valuable sources of probiotics and bioactive compounds.
- Understanding the gut microbiota's role is essential for developing novel strategies to improve metabolic health.
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