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Related Concept Videos

Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...

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Related Experiment Video

Updated: Jun 19, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
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Invasive Urinary Tract Aspergillosis: A Rare Entity.

Ahmed Amine Jaouahar1, Zakaria Chahbi2, Omar Maoujoud1

  • 1Nephrology and Hemodialysis, Avicenna Military Hospital, Marrakesh, MAR.

Cureus
|April 8, 2025
PubMed
Summary

A rare case of severe acute kidney injury (AKI) caused by invasive urinary aspergillosis is presented. Early diagnosis and antifungal therapy with voriconazole led to significant clinical improvement and kidney function recovery.

Keywords:
acute kidney injuryaspergillus fumigatushemodialysisobstructive uropathyurinary tract infections

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Area of Science:

  • Nephrology
  • Mycology
  • Infectious Diseases

Background:

  • Extracorporeal shock wave lithotripsy (ESWL) and ureteral stent placement are common procedures for renal calculi.
  • Urinary tract infections are typically bacterial, with fungal infections being less common.

Observation:

  • A 59-year-old male developed severe acute kidney injury (AKI) with anuria after ESWL and bilateral ureteral stent placement.
  • Despite interventions for presumed bacterial infection, the patient's condition rapidly worsened, with recurrent stent obstruction.

Findings:

  • Ureteroscopy-guided urine culture identified Aspergillus fumigatus, indicating invasive urinary aspergillosis.
  • Initiation of voriconazole therapy resulted in rapid clinical and biological improvement, including normalization of renal function.

Implications:

  • This case underscores the importance of considering fungal infections, specifically invasive urinary aspergillosis, in patients with unexplained obstructive AKI.
  • Early diagnosis and prompt antifungal treatment are crucial for successful management and recovery of renal function in such rare cases.